Compounding in pharmacy is defined as; the preparation, mixing, assembling, altering, packaging, and labeling of a drug or device or other article, as the result of a practitioner's order or in anticipation of such an order based on routine, regularly observed prescribing patterns.-USP-NF. At DuPont Circle Pharmacy, our highly skilled pharmacists are also trained to prepare medication formulations specific to your individual needs. Medications are compounded or prepared by our pharmacists at the request of a prescriber to;
- Create a patient specific dosage form (Example; capsules, suspensions, suppositories, creams, ointments, gels etc.) for a medication which is not commercially available.
- Re-formulate a medication without the color, dye, preservative/stabilizers which may be allergic to a particular patient.
- Combine several individual medications into one to dramatically improve patient compliance. We gladly reformulate or create a whole new preparation to make administration easier. For example we reconstitute to remove dyes, colors, preservatives etc. that may pose as allergens to our unique customers.
At DuPont Circle Pharmacy, we compound all the 3 categories of compounds to meet your individual needs; Simple: We make preparations that have a United States Pharmacopeia (USP) compounding monograph or that appears in a peer-reviewed journal article that contains specific quantities of all components, compounding procedure and equipment, and stability data for that formulation with appropriate Beyond Use Date (Expiration Date); or reconstituting or manipulating commercial products that may require the addition of one or more ingredients as directed by the manufacturer. Examples include Captopril Oral Solution, Indomethacin Topical Gel, and Potassium Bromide Oral Solution, Veterinary products and many more.
Moderate: We also prepare formulations that require special calculations or procedures (such as calibration of dosage unit mold cavities) to determine quantities of components per preparation or per individualized dosage units; or making a preparation for which stability data for that specific formulation are not available. Examples include Morphine Sulfate Suppositories, diphenhydramine hydrochloride troches, and mixing two or more manufactured cream products when the stability of the mixture is not known.
Complex: Finally, DuPont Circle Pharmacy formulates compounds that require special training, environment, facilities, equipment, and procedures to ensure appropriate therapeutic outcomes. Examples of possible complex preparation types include transdermal dosage forms, modified-release preparations, and some inserts and suppositories for systemic effects.